Features of the Structure of Cerebral Vessels in Persons who Died from Rupture of Cerebral Artery Aneurysm
https://doi.org/10.18499/2225-7357-2018-7-4-75-80
Abstract
The aim of the study is to define of variants of the Willi’s circle and also structural features of the vessel walls at the site of aneurysm location in people who died from aneurysms in the dead from their rupture to identify risk groups for cerebrovascular disease.
Material and methods. The structure of cerebral vessels of 8 people at the age from 17 to 69 of both sexes who died from subarachnoid hemorrhage of aneurysmal genesis was examined due to macro-microscopical and clinical methods. Histology slides of cerebral arterial walls of aneurysm area were stained with hematoxylin-eosin and Mallory’s technique and then were examined.
Results. Variants of the Willi’s circle and morphological features of vessel walls located in aneurysm formation area in people who died from aneurysm rupture are shown in the article
Conclusion. Not classic variants of Willi’s circle, fibromuscular dysplasia of the medial type and atherosclerotic changes of vessel walls contributes to aneurysm occurrence in cerebral vessels.
About the Authors
N. A. Trushel'
Belarusian State Medical University
Belarus
Minsk
Belarus
Minsk
N. I. Nechipurenko
Center of Neurology and Neurosurgery
Belarus
Minsk
Belarus
Minsk
R. R. Sidorovich
Center of Neurology and Neurosurgery
Belarus
Minsk
Belarus
Minsk
O. L. Zmachinskaya
Center of Neurology and Neurosurgery
Belarus
Minsk
Belarus
Minsk
I. V. Bokhan
City Clinical Pathoanatomical Bureau
Belarus
Minsk
Belarus
Minsk
References
1. Gabashvili V.M., Prokhorova E.S., Shakarishvili R.R. Epilepticheskie pripadki pri sosudistykh zabolevaniyakh golovnogo mozga [Epileptic seizures in vascular diseases of the brain]. Tbilisi: Metsniereba; 1986: 337 (in Russian).
2. Guzeva V.I. Epilepsiya i neepilepticheskie paroksizmal'nye sostoyaniya u detei [Epilepsy and nonepileptic paroxysmal conditions in children]. Moscow: Med. inform. agentstvo; 2007: 568 (in Russian).
3. Kurtusunov B.T. Strukturnye preobrazovaniya vertebro-bazilyarnoi sistemy v protsesse stareniya [Structural transformations of the vertebrobasilar system in the aging process]. Journal of theoretical and practical medicine. 2010; 8: 140–141 (in Russian).
4. Lipovetskii B.M., Vinogradova T.V. Lokalizatsiya sosudistykh porazhenii pri ateroskleroze i osobennosti lipidnogo sostava krovi [Localization of vascular lesions in atherosclerosis and peculiarities of blood lipid composition]. Therapeutic archive. 2002; 74(6): 55–57 (in Russian).
5. Markin S.P., Gorbunov A.B. Chastota zadnei trifurkatsii vnutrennei sonnoi arterii u bol'nykh tserebrovaskulyarnymi zabolevaniyami [The frequency of posterior trifurcation of the internal carotid artery in patients with cerebrovascular diseases]. IX all-Russian Congress of neurologists. Yaroslavl; 2006: 439 (in Russian).
6. Sidorovich R.R., Sel'skii M.S., Parkhach L.P., Zmachinskaya O.L. Sovremennye podkhody k diagnostike, profilaktike i lecheniyu sosudistogo spazma pri anevrizmaticheskom subarakhnoidal'nom krovoizliyanii [Modern approaches to the diagnosis, prevention and treatment of vascular spasm in aneurysmal subarachnoid hemorrhage]. Actual problems of neurology and neurosurgery: proceedings of the scientific conference. Minsk. 2014; 17: 200–209 (in Russian).
7. Trushel' N.A., Pivchenko P.G. Rol' morfologicheskogo i gemodinamicheskogo faktorov v aterogeneze sosudov villizieva kruga [The role of morphological and hemodynamic factors in atherogenesis of vessels of the Willis circle]. Minsk: Belarusian state medical University; 2013: 180 (in Russian).
8. Fomkina O.A. Morfologiya vnutricherepnykh chastei pozvonochnykh, bazilyarnykh i zadnikh mozgovykh arterii u vzroslykh lyudei razlichnogo vozrasta i pola : avtoref. dis. … kand. med. nauk [Morphology of intracranial vertebral, basilar and posterior cerebral arteries in adults of different age and sex: Cand. med. sci. diss. abs.]. Volgograd; 2006: 31 (in Russian).
9. Tsvibel' V.D., Pellerito D.S. Ul'trazvukovoe issledovanie sosudov [Ultrasound examination of vessels]. Moscow: Vidar; 2008: 646 (in Russian).
10. Acilan C., Serhatli M., Kacar O., Adiguzel Z., Tuncer A., Hayran M., Baysal K. Smooth muscle cells isolated from thoracic aortic aneurysms exhibit increased genomic damage, but similar tendency for apoptosis. DNA Cell Biol. 2012; 31(10): 1523–1534.21
11. Bisaria K.K., Anomalies of the posterior communicating artery and their potential clinical significance. J. Neurosurg. 1984; 60(3): 572–576.7
12. Cassot F., Vergeur V., Bossuet P., Hillen B., Zagzoule M., Marc-Vergnes J.P. Effects of anterior communicating artery diameter on cerebral hemodynamics in internal carotid artery disease. A model study. Circulation. 1995; 92(10): 3122– 3131.8
13. Chen X.L., Zhang Q., Zhao R., Medford R.M. Superoxide H2O2, and iron are required for TNFalpha-induced MCP-1 gene expression in endothelial cells role of Rac1 and NADPH oxidase. Am J Physiol Heart Circ Physiol. 2004; 286(3). H1001– H1007.17
14. Juric V., Chen C.C., Lau L.F. TNF alpha-induced apoptosis enabled by CCN1/CYR61: pathways of reactive oxygen species generation and cytochrome c release. PLoS One. 2012; 7(2): e31303.18
15. Kanematsu Y., Kanematsu M., Kurihara C., Tada Y., Tsou T.L., van Rooijen N., Lawton M.T., Young W.L., Liang E.I., Nuki Y., Hashimoto T. Critical roles of macrophages in the formation of intracranial aneurysm. Stroke. 2011; 42(1): 173–178.19
16. McCormick M.L., Gavrila D., Weintraub N.L. Role of oxidative stress in the pathogenesis of abdominal aortic aneurysms. Arterioscler Thromb Vasc Biol. 2007; 27(3): 461–469.20
17. Nixon A.M., Gunel M., Sumpio B.E. The critical role of hemodynamics in the development of cerebral vascular disease. J. Neurosurg. 2010; 112(6): 1240–1253.1
18. Sforza D.M., Putman C.M., Cebral J.R. Hemodynamics of Cerebral Aneurysms. Annu. Fluid Mech. 2009; 41(1): 91–107.2
19. Starke R.M., Chalouhi N., Ali M.S., Jabbour P.M., Tjoumakaris S.I., Gonzalez L.F., Rosenwasser R.H, Koch W.J., Dumont A.S. The Role of Oxidative Stress in Cerebral Aneurysm Formation and Rupture. Curr Neurovasc Res. 2013; 10 (3): 247– 255.16
20. Tateshima S., Omura H., Villablanca J.P., Vinuela F. Intra-aneurysmal hemodynamics during the growth of an unruptured aneurysm: in vitro study using longitudinal CT angiogram database. Am. J. Neiroradiol. 2007; 28: 622–627.3
21. Thomas S., Rich M.W. Epidemiology, pathophysiology, and prognosis of heart failure in the elderly. Heart Fail. Clin. 2007; 3(4): 381 – 387.
Review
For citations:
Trushel' N.A., Nechipurenko N.I., Sidorovich R.R., Zmachinskaya O.L., Bokhan I.V. Features of the Structure of Cerebral Vessels in Persons who Died from Rupture of Cerebral Artery Aneurysm. Journal of Anatomy and Histopathology. 2018;7(4):75-80. (In Russ.) https://doi.org/10.18499/2225-7357-2018-7-4-75-80
Views:
1366
Email this article 