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Morphofunctional Changes in Veins Used as Arteriovenous Fistula for Hemodialysis in Patients with Terminal Chronic Renal Failure on Continuous Hemodialysis

https://doi.org/10.18499/2225-7357-2017-6-1-21-24

Abstract

Using histological, histochemical, immunocytochemical and morphometric methods presented morphofunctional characteristics of veins used as arteriovenous fistula for hemodialysis in patients with terminal chronic renal failure are presented. It is revealed that in the veins, functioning for a long time (3-7 years) as arteriovenous fistula, the integrity of three tunics is preserved, accompanying with the complex of morphofunctional rearrangements. They are - change in thickness of vein tunics, relative thickening of the inner and middle tunics, increasing the content of smooth muscle and elastic membranes formation in the middle tunic, increasing the volume occupied by the vasa vasorum in the middle and outer tunics. The revealed changes testify arterialization of veins occurring under the influence of altered hemodynamic conditions.

About the Authors

E. N. Grigor'yev
Orenburg State Medical University, Orenburg, Russia
Russian Federation


N. N. Shevlyuk
Orenburg State Medical University, Orenburg, Russia
Russian Federation


V. S. Tarasenko
Orenburg State Medical University, Orenburg, Russia
Russian Federation


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Review

For citations:


Grigor'yev E.N., Shevlyuk N.N., Tarasenko V.S. Morphofunctional Changes in Veins Used as Arteriovenous Fistula for Hemodialysis in Patients with Terminal Chronic Renal Failure on Continuous Hemodialysis. Journal of Anatomy and Histopathology. 2017;6(1):21-24. (In Russ.) https://doi.org/10.18499/2225-7357-2017-6-1-21-24

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ISSN 2225-7357 (Print)