Morphological Features of Breast Tissue in Women of Different Age Groups in Normal and Fibrocystic Breast Disease

Abstract

Morphological features of breast tissue in normal and fibrocystic breast disease in women at different ages have been studied. After analyzing the data found that with age in healthy gland the proportion of fibrous tissue is constantly decreasing. The area of ducts increases in women between the ages of 17 to 40 years and subsequently remains at a high level. The number of lobules veraciously increases in the period from 31 to 40 years, then decreases, reaching a minimum in patients older than 66 years. In the group of women, suffering from fibrocystic breast disease, there is a high degree of fibrous and glandular components in all age periods. At the age of 17 to 30 years, the increase in the area of single and group ducts characterizes ductal hyperplasia, and the increase of lobules percentage - lobular hyperplasia. A study of quantitative morphological parameters (area of ducts, lobules; the proportion of fibrous, glandular and adipose tissue) of the breast tissue in different periods of life in normal conditions and in the presence of fibrocystic breast disease sustainable, age-dependent parameters were identified.