THE JUNCTIONAL ZONE OF THE UTERUS AND ADENOMYOSIS
https://doi.org/10.18499/2225-7357-2018-7-1-108-117
Abstract
In the structure of gynecological incidence adenomyosis occupies one of the leading places (12–50%) and occurs in women of reproductive age. However, the disease is diagnosed in late (III–IV) stages of development, on the material of hysterectomies. Diagnosis of adenomyosis at its early stages is possible taking into account the assessment of the status of the junctional zone of the uterus, information on which in the literature is little and contradictory. The position of the generality of the pathogenetic factor for adenomyosis / endometriosis syndrome advanced by a number of researchers in which the prevalence of hypertrophy of smooth junctional zone myocytes leads to the development of adenomyosis, and the invasion of the endometrium into the junctional zone to endometriosis suggests the involvement of this zone in the development of adenomyosis. It becomes obvious that knowledge about the structural and molecular organization of the junctional zone can be useful for optimizing the early clinical diagnosis of adenomyosis.
About the Authors
G. M. Mogil'naya
Kuban State Medical University
Russian Federation
Russian Federation
Krasnodar
I. I. Kutsenko
Kuban State Medical University
Russian Federation
Russian Federation
Krasnodar
A. N. Simovonik
Kuban State Medical University
Russian Federation
Russian Federation
Krasnodar
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Mogil'naya G.M., Kutsenko I.I., Simovonik A.N. THE JUNCTIONAL ZONE OF THE UTERUS AND ADENOMYOSIS. Journal of Anatomy and Histopathology. 2018;7(1):108-117. (In Russ.) https://doi.org/10.18499/2225-7357-2018-7-1-108-117
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