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Features of the Basic Patterns of the Rats’ Uterine Cervix Histogenesis During Postnatal Ontogenesis

https://doi.org/10.18499/2225-7357-2016-5-4-16-19

Abstract

Electron microscopic examination of the postnatal development of the tissues of the rats’ uterine cervix at the level of the sphincter was performed. It has been established that at the time of rats' birth the processes of histogenesis are not complete. Cervical sphincter becomes definitive structure only at the time of puberty. After birth and until the onset of puberty, the processes of cell proliferation, genetically programmed cell death, differentiation and integration continue in the uterine cervix. Intensity of these processes at different stages of postnatal development varies. The process of proliferation of cells, which is expressed maximally after birth of the animals, promotes the formation of layers of the uterine cervix and the walls of the myometrium. At the same time with active proliferation, signs of a specific differentiation and integration of tissues into a complex apparatus - cervical sphincter occurs. Histogenetic cell death in the cervical wall is observed throughout postnatal period, but it has a maximum value at the first month of life and in aging animals. In the first case, apoptosis plays a leading role in the formative processes; in the second case, it indicates a decrease in the functional activity of specialized tissues.

About the Authors

Yu. V. Grigor'yeva
Samara State Medical University, Samara, Russia
Russian Federation


G. N. Suvorova
Samara State Medical University, Samara, Russia
Russian Federation


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Review

For citations:


Grigor'yeva Yu.V., Suvorova G.N. Features of the Basic Patterns of the Rats’ Uterine Cervix Histogenesis During Postnatal Ontogenesis. Journal of Anatomy and Histopathology. 2016;5(4):16-19. (In Russ.) https://doi.org/10.18499/2225-7357-2016-5-4-16-19

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ISSN 2225-7357 (Print)