Histopathological Changes of the Periodontium and the Pulp of Teeth in the Area of Experimental Fracture of the Upper Jaw
https://doi.org/10.18499/2225-7357-2017-6-2-68-74
Abstract
The aim of the study was to evaluate the experimental histopathological changes in the periodontium and the dental pulp, located in the area of the upper jaw fracture. Material and methods. 28 adult guinea pigs were included in experimental-morphological study., Segmental fractures of the upper jaw by Le Fort I were modeled in animals by sawing the upper jaw with intraoral access to the front segment (with damage to the neurovascular infraorbital bundles), right and left lateral segments with interdental cross-sections (without damage of the neurovascular infraorbital bundles). In the control group were intact animals. The results of the study were processed using descriptive statistics. Results. Periodontium and the teeth pulp located in the fracture of the upper jaw undergo inflammatory and dystrophic changes. In the frontal incisors with fractures of the upper jaw with damage of neurovascular infraorbital bundles, these changes finish in a pulp necrosis of all investigated teeth by 28 days. The pulp necrosis occurred in 16 (9.5%) of 168 chewing teeth in fracture of the upper jaw, which indicates a high compensatory-adaptive possibilities of the pulp. Conclusions. Intact teeth in the fracture line of the upper jaw in most cases don’t complicate the healing, and can be saved after removal of the pulp.
About the Authors
S. V. Sirak
Stavropol State Medical University, Stavropol, Russia
Russian Federation
Russian Federation
E. V. Shchetinin
Stavropol State Medical University, Stavropol, Russia
Russian Federation
Russian Federation
I. V. Koshel'
Stavropol State Medical University, Stavropol, Russia
Russian Federation
Russian Federation
T. L. Kobylkina
Stavropol State Medical University, Stavropol, Russia
Russian Federation
Russian Federation
References
1. Будзинский Н. Э., Сирак С. В. Особенности лечения хронического верхушечного периодонтита с использованием мирамистина, иммобилизованного на композиционном полисорбе. Современные проблемы науки и образования. 2013; 3: 133.
2. Будзинский Н. Э., Сирак С. В., Максимова Е. М., Сирак А. Г. Определение антимикробной активности мирамистина, иммобилизованного на композиционном полисорбе, на микрофлору корневых каналов при остром и обострившемся хроническом периодонтите и процесс остеофикации в эксперименте на животных. Фундаментальные исследования. 2013; 7-3: 518-522.
3. Быков И. М., Сирак А. Г., Сирак С. В. Апробация нового зубного эликсира для профилактики кариеса зубов в условиях эксперимента. Современные проблемы науки и образования. 2013; 4: 128.
4. Григорьянц Л. А., Сирак С. В., Будзинский Н. Э. Некоторые особенности топографии нижнечелюстного канала. Клиническая стоматология. 2006; 1: 46-51.
5. Сирак С. В., Сирак А. Г., Копылова И. А., Бирагова А. К. Изучение морфологических изменений в пульпе зубов экспериментальных животных при лечении глубокого кариеса и острого очагового пульпита. Медицинский вестник Северного Кавказа. 2011; 23 (3): 29-33.
6. Сирак А. Г., Сирак С. В. Динамика репаративного дентиногенеза после лечения глубокого кариеса и острого очагового пульпита разработанной поликомпонентной лечебной пастой. Фундаментальные исследования. 2013; 5-2: 384-388.
7. Bruno K. F., Silva J. A., Silva T. A. et al. Characterization of inflammatory cell infiltrate in human dental pulpitis. International Endodontic Journal. 2010; 43 (11): 1013-1021. DOI: 10.1111/j.1365-2591.2010.01757.x
8. Cooper P. R., Holder M. J., Smith A. J. Inflammation and regeneration in the dentin-pulp complex: A double-edged sword. Journal of Endodontics. 2014; 40 (4): 46-51. DOI: 10.1016/j.joen.2014.01.021
9. Cordeiro M. M., Dong Z., Kaneko T. et al. Dental Pulp Tissue Engineering with Stem Cells from Exfoliated Deciduous Teeth. Journal of Endodontics. 2008; 34 (8): 962-969. DOI: 10.1016/j.joen.2008.04.009
10. Farhad A. R., Shokraneh A., Shekarchizade N. Regeneration or replacement? A case report and review of literature. Dental Traumatology. 2016; 32 (1): 71-79. DOI: 10.1111/edt.12200
11. Grimm W. D., Arnold W. A., Sirak S. W. et al. Сlinical, radiographic, and histological analyses after transplantation of crest-related palatal-derived ectomesenchymal stem cells (paldscs) for improving vertical alveolar bone augmentation in critical size alveolar defects. Journal of Clinical Periodontology. 2015; 42(17): 366b-366.
12. Na S., Zhang H., Huang F. et al. Regeneration of dental pulp/dentine complex with a three-dimensional and scaffold-free stem-cell sheet-derived pellet. Journal of Tissue Engineering and Regenerative Medicine. 2016; 10 (3): 261-270. DOI: 10.1002/term.1686
13. Renard E., Gaudin A., Bienvenu G. et al. Immune Cells and Molecular Networks in Experimentally Induced Pulpitis. Journal of Dental Research. 2016; 95 (2): 196-205. DOI: 10.1177/0022034515612086
14. Sirak S. V., Avanesyan R. A., Akkalaev A. B. et al. Мicrobiocenosis of oral cavity in patients with dental implants and over-dentures. Research Journal of Pharmaceutical, Biological and Chemical Sciences. 2014; 5 (5): 698-704.
15. Sirak S. V., Arutyunov A. V., Shchetinin E. V. et al. Сlinical and morphological substantiation of treatment of odontogenic cysts of the maxilla. Research Journal of Pharmaceutical, Biological and Chemical Sciences. 2014; 5 (5): 682-690.
16. Sirak S. W., Entschladen F., Shchetinin E. W., Grimm W. D. Low-level laser irradiation (810 nm) with toluidinblue photosensitizer promotes proliferation and differentiation of human oral fibroblasts evaluated in vitro. Journal of Clinical Periodontology. 2015; 42(S17): 328a-328.
17. Shchetinin E. V., Sirak S. V., Khodzhayan A.B. et al. Pathogenetic aspects of dental pulp pathology. Медицинский вестник Северного Кавказа. 2015; 2 (38): 187-191.
18. Thibodeau B., Trope M. Pulp revascularization of a necrotic infected immature permanent tooth: Case report and review of the literature. Pediatric Dentistry. 2007; 29 (1): 47-50.
19. Wigler R., Kaufman A. Y., Lin S. et al. Revascularization: A treatment for permanent teeth with necrotic pulp and incomplete root development. Journal of Endodontics. 2013; 39 (3): 319-326. DOI: 10.1016/j.joen.2012.11.014
Review
For citations:
Sirak S.V., Shchetinin E.V., Koshel' I.V., Kobylkina T.L. Histopathological Changes of the Periodontium and the Pulp of Teeth in the Area of Experimental Fracture of the Upper Jaw. Journal of Anatomy and Histopathology. 2017;6(2):68-74. (In Russ.) https://doi.org/10.18499/2225-7357-2017-6-2-68-74
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