Structural and Functional Interaction of B-cells of Pancreatic Islets and Exocrine Pancreatic Cells of Periinsular Acini in Animals with Different Glucose Tolerance
https://doi.org/10.18499/2225-7357-2016-5-2-56-60
Abstract
The article discusses the features of the interaction of B cells of the pancreatic islets and exocrine pancreatic cells of the periinsullar acini with normal and impaired tolerance to glucose in an organism. The data on the structural and functional reorganization of periinsular exocrine cells in animals with different state of carbohydrate metabolism depending on the phase and intensity of the secretory process of B cells of the pancreatic islets after physical loads was esteblished.
About the Authors
I. G. Stelnikova
Nizhny Novgorod State Medical Academy, Nizhny Novgorod, Russia
Russian Federation
Russian Federation
L. G. Nikonova
Nizhny Novgorod State Medical Academy, Nizhny Novgorod, Russia
Russian Federation
Russian Federation
References
1. Аметов А. С. В-клетка: секреция инсулина в норме и патологии / А.С. Аметов, О.М. Смирнова, М.В. Шестакова. М.: Медицина, 2005. 251с.
2. Губергриц Н. Б. Экзо- и эндокринная функции поджелудочной железы: один шаг от дуэта до дуэли / Н.Б. Губергриц, Н.В. Беляева // Сучасна гастроенторология. 2006. № 4. С. 18-30.
3. Дедов И. И. Алгоритмы специализированной клинической помощи больным сахарным диабетом: клинические рекомендации / И.И. Дедов, М.В. Шестакова // Сахарный диабет. 2015. №1. С. 2-111.
4. Bouwens L. Regulation of pancreatic beta-cellmass / L. Bouwens, I. Rooman // Physoil. Rev. 2005. Vol. 85. Р. 1255-1270.
5. De Fronzo R. A. New aspects of pathological genesis the diabetes mellitus / R.A. De Fronzo // Diabetes. 1998. Vol. 37. Р. 667-678.
6. Kobayshi S. Light and electron microscopic studies on the pancreatic acinar and islet cells in Xenopus laevis. Gunma / S. Kobayshi // J. Med. 1969. Vol. 17. Р. 60-103.
7. Singh J. Effects of islet hormones of nerve- mediated and acetylchotine-evoked secretory responses in the isolated pancreas of normal and diabetic rats / J. Singh, Е. Adeghate // Int. J. Mol. Med. 1998. Vol. 1. P. 627-634.
Review
For citations:
Stelnikova I.G., Nikonova L.G. Structural and Functional Interaction of B-cells of Pancreatic Islets and Exocrine Pancreatic Cells of Periinsular Acini in Animals with Different Glucose Tolerance. Journal of Anatomy and Histopathology. 2016;5(2):56-60. (In Russ.) https://doi.org/10.18499/2225-7357-2016-5-2-56-60
Views:
398
Email this article 