Predictive Modeling Morphological Changes of a Jejunum Mucous Membrane, Occur in the Context of Chronic Exposure Pulse Electromagnetic Fields

Abstract

The special importance of experimental and clinic-physiological studies is defined by insufficient study of electromagnetic radiations action mechanisms possessing high biological activity which maximum reaction can be shown in the remote terms, later 15 and even 35-45 years after the beginning of chronic action that is explained by increase of incidence frequency of organism various systems, and also decrease in compensatory reserves and acceleration of aging processes [5, 7]. Experiment is executed on white laboratory rats males, with initial age 4 months which underwent by chronic influence of electromagnetic fields impulses during 5, 7 and 10 months. Density of the induced currents in a body of rats made: 0.37, 0.7, 0.8 and 2.7 kA/ m² with frequency of 500, 100 and 50 impulses in a week (I/w) irrespective of their divisibility and lasting 15÷40 ns. Predictive modeling of a jejunum mucous membrane histoenzymological indicators serving as morphological equivalents of a functional state and reflecting age dynamics of possible development of chronic influence consequences of electromagnetic fields impulses various parameters testifies in general to preservation of the tendencies preceding the predicted period. However in chronic aspect of the forecast at a combination of the electromagnetic fields impulses some parameters in process of age changes increase restriction of the corpulent cells forms participating in local regulation of a homeostasis, and also essential changes of enzymes activity is observed.