anatomyЖурнал анатомии и гистопатологииJournal of Anatomy and Histopathology2225-7357N.N. Burdenko Voronezh State Medical University10.18499/2225-7357-2018-7-1-108-117anatomy-588Research ArticleОБЗОРНЫЕ СТАТЬИREVIEW ARTICLESПЕРЕХОДНАЯ ЗОНА МАТКИ И АДЕНОМИОЗTHE JUNCTIONAL ZONE OF THE UTERUS AND ADENOMYOSISМогильнаяГ. М.Mogil'nayaG. M.

Могальная Галина Мироновна – доктор медицинских наук, профессор, заведующая кафедрой гистологии с эмбриологией.

350063, Краснодар, ул. Седина, 4

Krasnodar

evglandr@mail.ruКуценкоИ. И.KutsenkoI. I.

Куценко Ирина Игоревна – доктор медицинских наук, профессор, заведующая кафедрой акушерства, гинекологии и перинатологии.

350063, Краснодар, ул. Седина, 4

Krasnodar

Luzum69@mail.ruСимовоникА. Н.SimovonikA. N.

Симовоник Анна Николаевна – аспирант кафедры гистологии с эмбриологией.

Krasnodar

anna.simovonik@gmail.comФГБОУ ВО «Кубанский государственный медицинский университет» Минздрава РоссииKuban State Medical University20182004201871108117Copyright © Могильная Г.М., Куценко И.И., Симовоник А.Н., 20182018Могильная Г.М., Куценко И.И., Симовоник А.Н.Mogil'naya G.M., Kutsenko I.I., Simovonik A.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://anatomy.elpub.ru/jour/article/view/588

В структуре гинекологической заболеваемости аденомиоз занимает одно из ведущих мест (12–50%) и встречается у женщин репродуктивного возраста. Однако заболевание диагностируется на поздних  (III–IV) стадиях развития, на материале гистерэктомий. Диагностика аденомиоза на его ранних стадиях возможна с учетом оценки статуса переходной зоны матки, сведения о которой в литературе немногочисленны и противоречивы. Выдвигаемое рядом исследователей положение общности патогенетического фактора для синдрома аденомиоз/эндометриоз, при котором превалирование гипертрофии гладких миоцитов переходной зоны приводит к развитию аденомиоза, а инвазия эндометрия в переходную зону – к эндометриозу, позволяет предположить участие этой зоны в развитии аденомиоза. При этом становится очевидным, что знания о структурной и молекулярной организации переходной зоны могут оказаться полезными для оптимизации ранней клинической диагностики аденомиоза.

In the structure of gynecological incidence adenomyosis occupies one of the leading places (12–50%) and occurs in women of reproductive age. However, the disease is diagnosed in late (III–IV) stages of development, on the material of hysterectomies. Diagnosis of adenomyosis at its early stages is possible taking into account the assessment of the status of the junctional zone of the uterus, information on which in the literature is little and contradictory. The position of the generality of the pathogenetic factor for adenomyosis / endometriosis syndrome advanced by a number of researchers in which the prevalence of hypertrophy of smooth junctional zone myocytes leads to the development of adenomyosis, and the invasion of the endometrium into the junctional zone to endometriosis suggests the involvement of this zone in the development of adenomyosis. It becomes obvious that knowledge about the structural and molecular organization of the junctional zone can be useful for optimizing the early clinical diagnosis of adenomyosis.

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The authors declare that there are no conflicts of interest present.