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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">anatomy</journal-id><journal-title-group><journal-title xml:lang="ru">Журнал анатомии и гистопатологии</journal-title><trans-title-group xml:lang="en"><trans-title>Journal of Anatomy and Histopathology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2225-7357</issn><publisher><publisher-name>N.N. Burdenko Voronezh State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18499/2225-7357-2016-5-4-57-60</article-id><article-id custom-type="elpub" pub-id-type="custom">anatomy-325</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL PAPERS</subject></subj-group></article-categories><title-group><article-title>Гистохимические особенности тканей пародонтально-десневого комплекса при пародонтопатиях у животных</article-title><trans-title-group xml:lang="en"><trans-title>Histochemical Properties of Parodontal-Gingival Complex Tissues in Animals with Parodontopathy</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сирак</surname><given-names>Сергей Владимирович</given-names></name><name name-style="western" xml:lang="en"><surname>Sirak</surname><given-names>S. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Щетинин</surname><given-names>Евгений Вячеславович</given-names></name><name name-style="western" xml:lang="en"><surname>Shchetinin</surname><given-names>E. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кошель</surname><given-names>Иван Владимирович</given-names></name><name name-style="western" xml:lang="en"><surname>Koshel'</surname><given-names>I. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сирак</surname><given-names>Алла Григорьевна</given-names></name><name name-style="western" xml:lang="en"><surname>Sirak</surname><given-names>A. G.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дыгов</surname><given-names>Эльдар Анатольевич</given-names></name><name name-style="western" xml:lang="en"><surname>Dygov</surname><given-names>E. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кобылкина</surname><given-names>Татьяна Леонидовна</given-names></name><name name-style="western" xml:lang="en"><surname>Kobylkina</surname><given-names>T. L.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Вафиади</surname><given-names>Марина Юрьевна</given-names></name><name name-style="western" xml:lang="en"><surname>Vafiadi</surname><given-names>M. Yu.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Одольский</surname><given-names>Аркадий Вячеславович</given-names></name><name name-style="western" xml:lang="en"><surname>Odol'skiy</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБОУ ВПО «Ставропольский государственный медицинский университет» Минздрава России</institution></aff><aff xml:lang="en"><institution>Stavropol State Medical University, Stavropol, Russia</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>28</day><month>12</month><year>2017</year></pub-date><volume>5</volume><issue>4</issue><fpage>57</fpage><lpage>60</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сирак С.В., Щетинин Е.В., Кошель И.В., Сирак А.Г., Дыгов Э.А., Кобылкина Т.Л., Вафиади М.Ю., Одольский А.В., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Сирак С.В., Щетинин Е.В., Кошель И.В., Сирак А.Г., Дыгов Э.А., Кобылкина Т.Л., Вафиади М.Ю., Одольский А.В.</copyright-holder><copyright-holder xml:lang="en">Sirak S.V., Shchetinin E.V., Koshel' I.V., Sirak A.G., Dygov E.A., Kobylkina T.L., Vafiadi M.Y., Odol'skiy A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://anatomy.elpub.ru/jour/article/view/325">https://anatomy.elpub.ru/jour/article/view/325</self-uri><abstract><p>В статье рассматриваются вопросы исследования гистохимических особенностей тканей пародонтально-десневого комплекса при пародонтопатиях в эксперименте на животных. Обнаружено, что введение пиримидиновых производных приводит к активизации синтеза РНК в клетках эпителия и соединительной ткани десны и к выраженной мобилизации и активации тучных клеток соединительной ткани. У обследованных животных отмечаются такие же изменения в распределении РНК, гликогена и кислых мукополисахаридов, что и при пародонтопатии у человека, что делает пародонтоз у парнокопытных весьма перспективной моделью для изучения пародонтопатии у человека.</p></abstract><trans-abstract xml:lang="en"><p>The article covers the histochemical features of parodontal-gingival complex tissues in parodontopathy in the experiment on animals. It was found that the introduction of pyrimidine derivatives leads to the activation of RNA synthesis in cells of epithelium and connective tissue of the gingiva and to the pronounced mobilization and activation of mast cells of connective tissue. The examined animals have the same changes in RNA, glycogen and acid mucopolysaccharides distribution as in humans with parodontopathy. This makes periodontal disease in cloven-hoofed a very promising model for studying parodontopathy in humans.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ткани пародонта</kwd><kwd>животные</kwd><kwd>эксперимент</kwd><kwd>periodontal tissues</kwd><kwd>animals</kwd><kwd>experiment</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Патофизиологические аспекты регенерации лунки удаленного зуба в эксперименте / Е. В. Щетинин [и др.] // Медицинский вестник Северного Кавказа. 2014. Т. 9, № 3 (35). С. 262-265. DOI: 10.14300/mnnc.2014.09073</mixed-citation><mixed-citation xml:lang="en">Патофизиологические аспекты регенерации лунки удаленного зуба в эксперименте / Е. В. Щетинин [и др.] // Медицинский вестник Северного Кавказа. 2014. 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