D.S. Sarkisov is an outstanding pathologist, scientist, researcher and philosopher. The works of D.S. Sarkisov do not lose their relevance in the 21st century, when medicine is moving far forward thanks to modern high-tech techniques. However, turning to the yellowed pages of D.S. Sarkisov’s works, one can find discussions on topical topics in medicine, such as the formulation of a diagnosis, which is impossible not to argue about today. Thanks to his philosophical approach to the organization of work, D.S. Sarkisov was able to create generalizing works, for example, in the field of experimental medicine, as a result of which we can, after reading one of his books, get a general idea of the current state of the issue. This rare ability to rise above all pressingmedical issues and the scientific data accumulated on them allowed Donat Semenovich to win the true respect and love of fellow clinicians and pathologists. I.V. Davydovsky had another equally extraordinary approach to work, the similarity of opinions with whom the authors discuss within the article. The desire for a comprehensive discussion of medical and scientific problems brought D.S. Sarkisov not only to face-to-face conferences, but also to the pages of well-deserved scientific publications. The discussions of D.S. Sarkisov and colleagues serve as a brilliant example of scientific dialogue. In personal and work relationships, D.S. Sarkisov also left an indelible impression on people who were lucky enough to communicate with him in person, as evidenced by touching articles dedicated to his memory.