anatomyЖурнал анатомии и гистопатологииJournal of Anatomy and Histopathology2225-7357N.N. Burdenko Voronezh State Medical University10.18499/2225-7357-2021-10-3-91-97anatomy-1377Research ArticleОБЗОРНАЯ СТАТЬЯREVIEW ARTICLEФункциональная морфология иммунных структур селезенки при действии повреждающих факторовFunctional Morphology of the Immune Structures of the Spleen Under the Influence of Damaging FactorsАлексееваН. Т.AlexeevaN. T.

Алексеева Наталия Тимофеевна

ул. Студенческая, 10, Воронеж, 394036

Nataliya Alexeeva

ul. Studencheskaya, 10, Voronezh, 394036

alexeevant@list.ruКварацхелияА. Г.KvaratskheliyaA. G.

Воронеж

Voronezh

СоколовД. А.SokolovD. A.

Воронеж

Voronezh

БахметА. А.BakhmetA. A.

Москва

Moscow

ПоповМ. В.PopovM. V.

Воронеж

Voronezh

ВердиянГ. Г.VerdiyanG. G.

Москва

Moscow

КлочковаС. В.KlochkovaS. V.

Москва

Moscow

ФГБОУ ВО «Воронежский государственный медицинский университет им. Н.Н. Бурденко» Минздрава РоссииN. N. Burdenko Voronezh State Medical UniversityФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова (Сеченовский Университет)» Минздрава РоссииFirst I. M. Sechenov Moscow State Medical University (Sechenov University)ФГАОУ ВО «Российский университет дружбы народов»; ГАУЗ «Московский научно-практический центр медицинской реабилитации, восстановительной и спортивной медицины ДЗМ»Peoples Friendship University of Russia (RUDN University); Moscow Scientific and Practical Center for Medical Rehabilitation, Rehabilitation and Sports Medicine2021200920211039197Copyright © Алексеева Н.Т., Кварацхелия А.Г., Соколов Д.А., Бахмет А.А., Попов М.В., Вердиян Г.Г., Клочкова С.В., 20212021Алексеева Н.Т., Кварацхелия А.Г., Соколов Д.А., Бахмет А.А., Попов М.В., Вердиян Г.Г., Клочкова С.В.Alexeeva N.T., Kvaratskheliya A.G., Sokolov D.A., Bakhmet A.A., Popov M.V., Verdiyan G.G., Klochkova S.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://anatomy.elpub.ru/jour/article/view/1377

В последние годы существенно вырос интерес к изучению морфофункциональных особенностей органов иммунной системы. Иммунная система вносит существенный вклад в процессы гомеостаза и поддержания здоровья организма. Иммунитет определяет состояние устойчивости организма к инфекционным факторам. При этом, особый интерес представляет селезенка как иммунный орган, поскольку иммунная система человека и животных является одной из наиболее чувствительных систем организма, быстро реагирующей на любые воздействия. В статье представлен обзор литературы, посвященный современным представлениям о морфофункциональной организации селезенки в связи с выполняемыми функциями, а также влиянию повреждающих факторов на изменения морфофункциональных показателей компонентов селезенки.

In recent years, interest in the study of the morphological and functional characteristics of the organs of the immune system has grown significantly. The immune system makes a significant contribution to the processes of homeostasis and maintaining the health of the organism. Immunity determines the state of the body's resistance to infectious factors. At the same time, the spleen is of particular interest as an immune organ, since the immune system of humans and animals is one of the most sensitive systems of the body, which quickly reacts to any influences. The article presents a literature review devoted to modern concepts of the morphofunctional organization of the spleen in connection with the functions performed, as well as the influence of damaging factors on changes in the morphofunctional parameters of the components of the spleen.

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The authors declare that there are no conflicts of interest present.