anatomyЖурнал анатомии и гистопатологииJournal of Anatomy and Histopathology2225-7357N.N. Burdenko Voronezh State Medical University10.18499/2225-7357-2020-9-3-22-27anatomy-1153Research ArticleОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯORIGINAL PAPERSРазвитие крестцовых позвонков у зародышей человекаDevelopment of sacral vertebrae in human embryos and fetusesКабакС. Л.KabakS. L.

проспект Дзержинского, 83, Минск, 220116, Республика Беларусь

prospekt Dzerzhinskogo, 83, 220116, Belarus

ЗаточнаяВ. В.ZatochnayaV. V.

Минск

Minsk

УО «Белорусский государственный медицинский университет»Belarusian State Medical University202009102020932227Copyright © Кабак С.Л., Заточная В.В., 20202020Кабак С.Л., Заточная В.В.Kabak S.L., Zatochnaya V.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://anatomy.elpub.ru/jour/article/view/1153

Цель исследования – установить особенности органогенеза и гистогенеза крестцовых позвонков у зародышей человека, предопределяющие анатомическое строение крестца в постнатальном онтогенезе.

Материал и методы

Материал и методы. Были изучены серийные срезы эмбрионов человека 17–23-й стадий из виртуальной эмбриологической коллекции Карнеги, тотальные препараты и серийные срезы поясничнокрестцовой области позвоночника плодов человека 8–20-недельного возраста без видимых аномалий развития. Гистологические срезы окрашивали гематоксилином и эозином; тотальные препараты – ализариновым красным и альциановым синим. Кроме того, были исследованы 19 крестцов взрослых людей из анатомической коллекции Белорусского государственного медицинского университета.

Результаты

Результаты. Нами установлено, что консолидация закладок верхних крестцовых позвонков начинается на ранних этапах эмбриогенеза слиянием их реберно-поперечных отростков. На протяжении первой половины внутриутробного развития дуги и суставные отростки смежных позвонков остаются обособленными друг от друга. В отличие от других сегментов позвоночного столба в закладках верхних крестцовых позвонков формируется по пять первичных центров окостенения.

The aim of the study is to define the features of organogenesis and histogenesis of sacral vertebrae in human embryos, which predetermine the anatomical structure of the sacrum in postnatal ontogenesis.

Material and methods

Material and methods. The authors studied human embryo serial sections at 17–23 stages from the Carnegie virtual embryological collection, total preparations and serial sections of the lumbosacral region of the fetal spine at 8–20 weeks of gestation without visible developmental anomalies. Histological sections were stained with hematoxylin and eosin; total preparations were stained with alizarin red and alcian blue. In addition, the study included 19 adult sacra from the anatomical collection of the Belarusian State Medical University.

Results

Results. It was found that consolidation of the anlages of the upper sacral vertebrae starts at the early stages of embryogenesis by the fusion of their costal-transverse processes. During the first half of intrauterine development, the arch and articular processes of the adjacent vertebrae remain separate from each other. In contrast to other segments of the spinal column, five primary centers of ossification are formed in the anlages of the upper sacral vertebrae

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The authors declare that there are no conflicts of interest present.