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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">anatomy</journal-id><journal-title-group><journal-title xml:lang="ru">Журнал анатомии и гистопатологии</journal-title><trans-title-group xml:lang="en"><trans-title>Journal of Anatomy and Histopathology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2225-7357</issn><publisher><publisher-name>N.N. Burdenko Voronezh State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18499/2225-7357-2020-9-1-86-93</article-id><article-id custom-type="elpub" pub-id-type="custom">anatomy-1074</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW ARTICLES</subject></subj-group></article-categories><title-group><article-title>Особенности репаративных гистогенезов при использовании биопластических материалов</article-title><trans-title-group xml:lang="en"><trans-title>Features of Reparative Histogenesis in Bioplastic Material Application</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шевлюк</surname><given-names>Н. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Shevlyuk</surname><given-names>N. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шевлюк Николай Николаевич.</p><p>ул. Советская, 6, г. Оренбург, 460000, Российская Федерация.</p></bio><bio xml:lang="en"><p>Nikolai Shevlyuk.</p><p>ul. Sovetskaya, 6, Orenburg, 460000, Russian Federation.</p></bio><email xlink:type="simple">k_histology@orgma.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гатиатуллин</surname><given-names>И. З.</given-names></name><name name-style="western" xml:lang="en"><surname>Gatiatullin</surname><given-names>I. Z.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Оренбург.</p></bio><bio xml:lang="en"><p>Orenburg.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Стадников</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Stadnikov</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Оренбург.</p></bio><bio xml:lang="en"><p>Orenburg.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Оренбургский государственный медицинский университет» Минздрава России</institution></aff><aff xml:lang="en"><institution>Orenburg State Medical University</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>01</day><month>04</month><year>2020</year></pub-date><volume>9</volume><issue>1</issue><fpage>86</fpage><lpage>93</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шевлюк Н.Н., Гатиатуллин И.З., Стадников А.А., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Шевлюк Н.Н., Гатиатуллин И.З., Стадников А.А.</copyright-holder><copyright-holder xml:lang="en">Shevlyuk N.N., Gatiatullin I.Z., Stadnikov A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://anatomy.elpub.ru/jour/article/view/1074">https://anatomy.elpub.ru/jour/article/view/1074</self-uri><abstract><p>В современной медицине широко используются различные биосовместимые материалы (на основе биодеградируемых естественных биополимеров – коллагена, гиалуроновой кислоты, хитина, хитозана и др.), прежде всего, для целей восстановительной и пластической хирургии. Разработка этих материалов и внедрение их в клиническую практику является чрезвычайно актуальной задачей регенеративной биологии и медицины. Одним из важнейших свойств биопластических материалов является их способность подвергаться биодеградации и постепенно замещаться собственными тканями реципиента. При этом промежуточные и конечные продукты метаболизма этих материалов должны включаться в естественные биохимические циклы организма без их системного и локального накопления, а продукты деградации не должны быть токсичными. Биопластические материалы способны также служить носителем биологиче- ски активных веществ, например, факторов роста и морфогенетических белков, антибактериальных веществ, а также фармакологических препаратов, влияющих на скорость регенерации. Сформированная трехмерная пористая структура новых материалов, морфологически похожая на структуру тканей организма, позволяет им обеспечивать миграцию фибробластических клеток, врастание кровеносных сосудов в зону, занимаемую этим материалом, то есть, они могут служить каркасом (матрицей), на основе которого формируются гистио- и органотипические регенераты в различных органах. Многие биопластические материалы обладают способностью обеспечивать усиление ангиогенеза, а также способны активизировать процессы пролиферации и цитодифференцировки эпителиоцитов и клеток фибробластического дифферона соединительной ткани, что приводит к формированию в зоне трансплантата молодой соединитель- ной ткани и эпителизации повреждения органов. Таким образом, биосовместимые и биодеградируемые полимеры способны стимулировать репаративные гистогенезы, обеспечивая оптимальные условия для формирования гистио- и органотипических регенератов различных тканей и органов.</p></abstract><trans-abstract xml:lang="en"><p>In modern medicine, various biocompatible materials (based on biodegradable natural biopolymers – collagen, hyaluronic acid, chitin, chitosan, etc.) are widely used, primarily for the purposes of reconstructive and plastic surgery. The development of these materials and their introduction into clinical practice is an extremely urgent task of regenerative biology and medicine. One of the most important properties of bioplastic materials is their ability to undergo biodegradation and gradually be replaced by the recipient's proper tissues. In this case, the intermediate and final metabolic products of these materials should be included in the natural biochemical cycles of the body without their systemic and local accumulation, and degradation products should lack the toxicity effect. Bioplastic materials can also serve as carriers of biologically active substances, for example, growth factors and morphogenetic proteins, antibacterial substances, as well as pharmacological agents that affect the rate of regeneration. The designed three-dimensional porous structure of new materials, morphologically similar to the structure of body tissues, allows them to ensure the migration of fibroblastic cells, the growth of blood vessels in the area occupied by this material, that is, they can serve as a skeleton (matrix), a basis for histio- and organotypic regenerates developing in various organs. Many bioplastic materials have the ability to enhance angiogenesis, and are also able to activate proliferation and cytodifferentiation of epithelial cells and fibroblast differentiation cells of the connective tissue, which leads to the formation of young connective tissue in the transplant zone and epithelization of organ damage. Thus, biocompatible and biodegradable polymers are able to stimulate reparative histogenesis, providing optimal conditions for the formation of histio- and organotypic regenerates of various tissues and organs.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>биосовместимые материалы</kwd><kwd>биополимеры</kwd><kwd>реконструктивная хирургия</kwd><kwd>фибробласты</kwd><kwd>регенерация</kwd><kwd>соединительная ткань</kwd><kwd>клеточная дифференцировка</kwd><kwd>эпителиальные клетки</kwd></kwd-group><kwd-group xml:lang="en"><kwd>biocompatible materials</kwd><kwd>biopolymers</kwd><kwd>reconstructive surgical procedures</kwd><kwd>fibroblasts</kwd><kwd>regeneration</kwd><kwd>connective tissue</kwd><kwd>cell differentiation</kwd><kwd>epithelial cells</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Арсеньев П.А., Саратовская Н.В. Синтез и исследование материалов на основе гидрооксиа- патита кальция. Стоматология. 1996;5:74–9 [Arsen'ev PA, Saratovskaya NV. Sintez i issledovanie materialov na osnove gidrooksiapatita kal'tsiya. Stomatologiya. 1996;5:74–9] (in Russian).</mixed-citation><mixed-citation xml:lang="en">Арсеньев П.А., Саратовская Н.В. Синтез и исследование материалов на основе гидрооксиа- патита кальция. Стоматология. 1996;5:74–9 [Arsen'ev PA, Saratovskaya NV. Sintez i issledovanie materialov na osnove gidrooksiapatita kal'tsiya. Stomatologiya. 1996;5:74–9] (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Бежин А.И., Липатов В.А., Фрончек Э.В., Гри- горьян А.Ю., Наимзада М.Д.З. Применение хитозан-коллагенового комплекса с нано- частицами серебра и химотрипсином в лечении гнойно-некротических ран. Вестник новых медицинских технологий. 2019; 26(5): 23–8 [Bezhin AI, Lipatov VA, Fronchek EV, Grigoryan AYu, Naimzada MDZ. Application chitosancollagen complex nano-particles of silver and chymotrypsin in the treatment of purulent necrotic wounds. Journal of New Medical Technologies. 2019; 26(5): 23–8] (in Russian).</mixed-citation><mixed-citation xml:lang="en">Бежин А.И., Липатов В.А., Фрончек Э.В., Гри- горьян А.Ю., Наимзада М.Д.З. Применение хитозан-коллагенового комплекса с нано- частицами серебра и химотрипсином в лечении гнойно-некротических ран. Вестник новых медицинских технологий. 2019; 26(5): 23–8 [Bezhin AI, Lipatov VA, Fronchek EV, Grigoryan AYu, Naimzada MDZ. Application chitosancollagen complex nano-particles of silver and chymotrypsin in the treatment of purulent necrotic wounds. Journal of New Medical Technologies. 2019; 26(5): 23–8] (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Гатиатуллин И.З., Шевлюк Н.Н., Третьяков А.А., Фадеев С.Б. Морфофункциональная характеристика репаративного гистогенеза при лечении гнойных ран кожи. Практическая медицина. 2019; 17(1): 117–9 [Gatiatullin IZ, Shevlyuk NN, Tretyakov AA, Fadeev SB. Morphofunctional characteristics of reparative histogenesis in the treatment of purulent skin wounds. Practical Medicine. 2019; 17(1): 117–9] (in Russian).</mixed-citation><mixed-citation xml:lang="en">Гатиатуллин И.З., Шевлюк Н.Н., Третьяков А.А., Фадеев С.Б. Морфофункциональная характеристика репаративного гистогенеза при лечении гнойных ран кожи. Практическая медицина. 2019; 17(1): 117–9 [Gatiatullin IZ, Shevlyuk NN, Tretyakov AA, Fadeev SB. Morphofunctional characteristics of reparative histogenesis in the treatment of purulent skin wounds. Practical Medicine. 2019; 17(1): 117–9] (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Забиров Р.А., Рахматуллин Р.Р. Пластика дефектов барабанной перепонки биопластическим материалом «Гиаматрикс». Оренбург: ДИМУР; 2013. 144 [Zabirov RA, Rakhmatullin RR. Plastika defektov barabannoi pereponki bioplasticheskim materialom «Giamatriks». Orenburg: DIMUR; 2013. 144] (in Russian).</mixed-citation><mixed-citation xml:lang="en">Забиров Р.А., Рахматуллин Р.Р. Пластика дефектов барабанной перепонки биопластическим материалом «Гиаматрикс». Оренбург: ДИМУР; 2013. 144 [Zabirov RA, Rakhmatullin RR. Plastika defektov barabannoi pereponki bioplasticheskim materialom «Giamatriks». Orenburg: DIMUR; 2013. 144] (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Зиновьев Е.В., Рахматуллин Р.Р., Османов К.Ф., Жилин К.К., Нестеров Ю.В., Якимов Д.К. Механотопография и биологические свойства гистоэквивалент-биопластического материала на основе гидроколлоида гиалуроновой кислоты. Вестник Российской военно-медицинской академии. 2013; 4(44):200–4 [Zinovyev EV, Rahmatullin RR, Osmanov KF, Zhilin АA, Nesterov YuV, Yakimov DK. Mehanotopography and biological properties of histoecvivalentbioplastic material based on hydrocolloids hyaluronic acid. Herald of the Russian Military Medical Academy. 2013; 4(44):200–4] (in Russian).</mixed-citation><mixed-citation xml:lang="en">Зиновьев Е.В., Рахматуллин Р.Р., Османов К.Ф., Жилин К.К., Нестеров Ю.В., Якимов Д.К. Механотопография и биологические свойства гистоэквивалент-биопластического материала на основе гидроколлоида гиалуроновой кислоты. Вестник Российской военно-медицинской академии. 2013; 4(44):200–4 [Zinovyev EV, Rahmatullin RR, Osmanov KF, Zhilin АA, Nesterov YuV, Yakimov DK. Mehanotopography and biological properties of histoecvivalentbioplastic material based on hydrocolloids hyaluronic acid. Herald of the Russian Military Medical Academy. 2013; 4(44):200–4] (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Кадыров Р.З. Экспериментальная кератопластика амнионом и биоматериалом «Аллоплант». Вестник Оренбургского государственного университета. 2013; 4(153):113–5 [Kadyrov RZ. experimental keratoplasty with amnion and Alloplant biomaterial. Vestnik of the Orenburg State University. 2013; 4(153):113–5] (in Russian).</mixed-citation><mixed-citation xml:lang="en">Кадыров Р.З. Экспериментальная кератопластика амнионом и биоматериалом «Аллоплант». Вестник Оренбургского государственного университета. 2013; 4(153):113–5 [Kadyrov RZ. experimental keratoplasty with amnion and Alloplant biomaterial. Vestnik of the Orenburg State University. 2013; 4(153):113–5] (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Канюков В.Н. Стадников А.А., Трубина О.М., Рахматуллин Р.Р., Яхина О.М. Гистоэквивалент биопластического материала в офтальмологии. Оренбург. 2014. 174 [Kanyukov V.N. Stadnikov A.A., Trubina O.M., Rakhmatullin R.R., Yakhina O.M. Gistoekvivalent bioplasticheskogo materiala v oftal'mologii. Orenburg. 2014. 174] (in Russian).</mixed-citation><mixed-citation xml:lang="en">Канюков В.Н. Стадников А.А., Трубина О.М., Рахматуллин Р.Р., Яхина О.М. Гистоэквивалент биопластического материала в офтальмологии. Оренбург. 2014. 174 [Kanyukov V.N. Stadnikov A.A., Trubina O.M., Rakhmatullin R.R., Yakhina O.M. Gistoekvivalent bioplasticheskogo materiala v oftal'mologii. Orenburg. 2014. 174] (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Каралкин П.А., Грядунова А.А., Перейра Ф.Д.А.С., Парфенов В.А., и др. Морфологический анализ in vivo биосовместимости напечатанного протеза ушной раковины. Морфология. 2017; 152(6):61–6 [Karalkin P.A., Gryadunova A.A., Pereira F. D. A. S., Parfyonov V.A., et al. Morphological analysis of in vivo biocompatibility of printed auricle prosthesis. Morfologiia. 2017; 152(6):61–6] (in Russian).</mixed-citation><mixed-citation xml:lang="en">Каралкин П.А., Грядунова А.А., Перейра Ф.Д.А.С., Парфенов В.А., и др. Морфологический анализ in vivo биосовместимости напечатанного протеза ушной раковины. Морфология. 2017; 152(6):61–6 [Karalkin P.A., Gryadunova A.A., Pereira F. D. A. S., Parfyonov V.A., et al. Morphological analysis of in vivo biocompatibility of printed auricle prosthesis. Morfologiia. 2017; 152(6):61–6] (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Лекишвили М.В., Склянчук Е.Д., Акатов В.С., Очкуренко А.А., Гурьев В.В., Рагинов И.С., и др. Костнопластические остеоиндуктивные материалы в травматологии и ортопедии. Гений ортопедии. 2015; 4:61–7 [Lekishvili MV, Sklianchuk ED, Akatov VS, Ochkurenko AA, Gur’ev VV, Raginov IS, et al. Osteoplastic osteoinductive materials in traumatology and orthopaedics. Genij Ortopedii. 2015 Dec;(4):61–7] (in Russian). doi: 10.18019/1028-4427-2015-4-61-67</mixed-citation><mixed-citation xml:lang="en">Лекишвили М.В., Склянчук Е.Д., Акатов В.С., Очкуренко А.А., Гурьев В.В., Рагинов И.С., и др. Костнопластические остеоиндуктивные материалы в травматологии и ортопедии. Гений ортопедии. 2015; 4:61–7 [Lekishvili MV, Sklianchuk ED, Akatov VS, Ochkurenko AA, Gur’ev VV, Raginov IS, et al. Osteoplastic osteoinductive materials in traumatology and orthopaedics. Genij Ortopedii. 2015 Dec;(4):61–7] (in Russian). doi: 10.18019/1028-4427-2015-4-61-67</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Литвинов С.Д., Краснов А.Ф., Куликов А.Н. Применение композита «ЛитАр» в случае замедленной консолидации перелома и ложного сустава. Бюллетень ВСНЦ СО РАМН. 2006; 5(51):122–7 [Litvinov SD, Krasnov AF, Kulikov AN. The application of the composite material Litar in the case of a slowed up consolidation of fracture (ununited fracture) and of a false joint (pseudarthrosis). Bulletin of the East Siberian Scientific Center SB RAMS. 2006; 5(51):122–7] (in Russian).</mixed-citation><mixed-citation xml:lang="en">Литвинов С.Д., Краснов А.Ф., Куликов А.Н. Применение композита «ЛитАр» в случае замедленной консолидации перелома и ложного сустава. Бюллетень ВСНЦ СО РАМН. 2006; 5(51):122–7 [Litvinov SD, Krasnov AF, Kulikov AN. The application of the composite material Litar in the case of a slowed up consolidation of fracture (ununited fracture) and of a false joint (pseudarthrosis). Bulletin of the East Siberian Scientific Center SB RAMS. 2006; 5(51):122–7] (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Макеева Г.А. Применение амниона и твердой мозговой оболочки для барьерной пластики при хирургическом лечении птеригиума. Офтальмологический журнал. 1983; 2: 104–6 [Makeeva GA. Primenenie amniona i tverdoi mozgovoi obolochki dlya bar'ernoi plastiki pri khirurgicheskom lechenii pterigiuma. Ophthalmological Journal. 1983; 2: 104–6] (in Russian).</mixed-citation><mixed-citation xml:lang="en">Макеева Г.А. Применение амниона и твердой мозговой оболочки для барьерной пластики при хирургическом лечении птеригиума. Офтальмологический журнал. 1983; 2: 104–6 [Makeeva GA. Primenenie amniona i tverdoi mozgovoi obolochki dlya bar'ernoi plastiki pri khirurgicheskom lechenii pterigiuma. Ophthalmological Journal. 1983; 2: 104–6] (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Мулдашев Э.Р. Предисловие к книге: Очерки трансплантации тканей. Уфа: Полиграфком-бинат: 2003: 4–6 [Muldashev E.R. Predislovie k knige: Ocherki transplantatsii tkanei. Ufa: Poligrafkombinat: 2003: 4–6] (in Russian).</mixed-citation><mixed-citation xml:lang="en">Мулдашев Э.Р. Предисловие к книге: Очерки трансплантации тканей. Уфа: Полиграфком-бинат: 2003: 4–6 [Muldashev E.R. Predislovie k knige: Ocherki transplantatsii tkanei. Ufa: Poligrafkombinat: 2003: 4–6] (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Мулдашев Э.Р., Муслимов С.А., Нигматуллин Р.Т. Регенеративная хирургия на основе трансплантационных технология Аллоплант. Морфология. 2002; 121(2–3):109 [Muldashev ER, Muslimov SA, Nigmatullin RT. Regenerativnaya khirurgiya na osnove transplantatsionnykh tekhnologiya Alloplant. Morfologiia. 2002; 121(2–3):109] (in Russian).</mixed-citation><mixed-citation xml:lang="en">Мулдашев Э.Р., Муслимов С.А., Нигматуллин Р.Т. Регенеративная хирургия на основе трансплантационных технология Аллоплант. Морфология. 2002; 121(2–3):109 [Muldashev ER, Muslimov SA, Nigmatullin RT. Regenerativnaya khirurgiya na osnove transplantatsionnykh tekhnologiya Alloplant. Morfologiia. 2002; 121(2–3):109] (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Мухаммедов Х.Б.М., Шевлюк Н.Н., Третьяков А.А., Фадеев С.Б. Анализ особенностей гистогенеза соединительной ткани при использовании биодеградируемого материала в условиях влияния окситоцина (экспериментально-гистологическое исследование). Морфология. 2017; 152(5):88–91 [Mukhammedov KhBM, Shevlyuk NN, Tretyakov AA, Fadeyev SB. Analysis of the peculiarities of connective tissue histogenesis with the use of biodegradable material under the influence of oxytocin (an experimental histological study). Morfologiia. 2017; 152(5):88–91] (in Russian).</mixed-citation><mixed-citation xml:lang="en">Мухаммедов Х.Б.М., Шевлюк Н.Н., Третьяков А.А., Фадеев С.Б. Анализ особенностей гистогенеза соединительной ткани при использовании биодеградируемого материала в условиях влияния окситоцина (экспериментально-гистологическое исследование). Морфология. 2017; 152(5):88–91 [Mukhammedov KhBM, Shevlyuk NN, Tretyakov AA, Fadeyev SB. Analysis of the peculiarities of connective tissue histogenesis with the use of biodegradable material under the influence of oxytocin (an experimental histological study). Morfologiia. 2017; 152(5):88–91] (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Новицкий И.Я. Место трансплантации амниотической оболочки в лечении заболеваний роговицы, сопровождающихся ее неоваскуляризвцией. Вестник офтальмологии. 2003; 6:9–</mixed-citation><mixed-citation xml:lang="en">Новицкий И.Я. Место трансплантации амниотической оболочки в лечении заболеваний роговицы, сопровождающихся ее неоваскуляризвцией. Вестник офтальмологии. 2003; 6:9–</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">[Novitskii IYa. A place for transplanting the amniotic sac in corneal pathologies concomitantwith corneal neovascularization. Vestnik oftal'mologii. 2003; 6:9–12] (in Russian).</mixed-citation><mixed-citation xml:lang="en">[Novitskii IYa. A place for transplanting the amniotic sac in corneal pathologies concomitantwith corneal neovascularization. Vestnik oftal'mologii. 2003; 6:9–12] (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Нузов Б.Г., Стадников А.А., Нузова О.Б. Оп- тимизация репаративной регенерации тканей. М.: Медицина; 2012. 200 [Nuzov BG, Stadnikov AA, Nuzova OB. Optimizatsiya reparativnoi regeneratsii tkanei. Moscow: Meditsina; 2012. 200] (in Russian).</mixed-citation><mixed-citation xml:lang="en">Нузов Б.Г., Стадников А.А., Нузова О.Б. Оп- тимизация репаративной регенерации тканей. М.: Медицина; 2012. 200 [Nuzov BG, Stadnikov AA, Nuzova OB. Optimizatsiya reparativnoi regeneratsii tkanei. Moscow: Meditsina; 2012. 200] (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Патлатая Н.Н., Левенец А.А., Большаков И.Н. Опыт применения «Бол-хитала» – нового материала для оптимизации остеогенеза в сто- матологии. Сибирское медицинское обозрение. 2009; 5(59): 84–6 [Patlataya NN, Levenest AA, Bol'shakov IN. Application of bol-hital - a new material for optimization of osteogenesis in dentistry. Siberian Medical Review. 2009; 5(59): 84–6] (in Russian).</mixed-citation><mixed-citation xml:lang="en">Патлатая Н.Н., Левенец А.А., Большаков И.Н. Опыт применения «Бол-хитала» – нового материала для оптимизации остеогенеза в сто- матологии. Сибирское медицинское обозрение. 2009; 5(59): 84–6 [Patlataya NN, Levenest AA, Bol'shakov IN. Application of bol-hital - a new material for optimization of osteogenesis in dentistry. Siberian Medical Review. 2009; 5(59): 84–6] (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Перова Н.В., Порунова Ю.В., Урьяш В.Ф., Фаминская Л.А. Биодеградируемый коллагенсодержащий матрикс Сферогель для биоискусственных органов и тканей. Вестник трансплантологии и искусственных органов. 2003; 4:46–</mixed-citation><mixed-citation xml:lang="en">Перова Н.В., Порунова Ю.В., Урьяш В.Ф., Фаминская Л.А. Биодеградируемый коллагенсодержащий матрикс Сферогель для биоискусственных органов и тканей. Вестник трансплантологии и искусственных органов. 2003; 4:46–</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">[Perova NV, Porunova YuV, Uryash VF, Faminskaja LA. Biodegraded collagen-contain Sferogel TM matrix for bioartificial bodies. Vestnik transplantologii i iskusstvennyh organov. 2003; 4:46–9] (in Russian).</mixed-citation><mixed-citation xml:lang="en">[Perova NV, Porunova YuV, Uryash VF, Faminskaja LA. Biodegraded collagen-contain Sferogel TM matrix for bioartificial bodies. Vestnik transplantologii i iskusstvennyh organov. 2003; 4:46–9] (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Рахматуллин Р.Р., Забиров Р.А., Акимов А.В., Гарифзянова С.М. Разработка наноструктурированного биопластического материала «Гиаматрикс» для ото- и ринохирургии. Российская оториноларингология. 2011; 4(53):128–31 [Rakhmatullin RR, Zabirov RA, Akimov AV, Garifzynova SM. Working out nanoreticulated of the bioplastic material hyamatrix for oto- and rhinosurgery. Russian otorhinolaryngology. . 2011; 4(53):128–31] (in Russian).</mixed-citation><mixed-citation xml:lang="en">Рахматуллин Р.Р., Забиров Р.А., Акимов А.В., Гарифзянова С.М. Разработка наноструктурированного биопластического материала «Гиаматрикс» для ото- и ринохирургии. Российская оториноларингология. 2011; 4(53):128–31 [Rakhmatullin RR, Zabirov RA, Akimov AV, Garifzynova SM. Working out nanoreticulated of the bioplastic material hyamatrix for oto- and rhinosurgery. Russian otorhinolaryngology. . 2011; 4(53):128–31] (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Семченко В.В., Ерениев С.И., Степанов С.С., Дыгай А.М., Ощепков В.Г., Лебедев И.Н. Регенеративная биология и медицины. Книга 1. Генные технологии и клонирование. Под ред. В.П. Пузырева, К.Н.Ярыгина, В.Н.Ярыгина, В.В.Семченко. Омск-Москва-Томск: Омская областная типография; 2012. 296 [Semchenko VV, Ereniev SI, Stepanov SS, Dygai AM, Oshchepkov VG, Lebedev IN. Regenerativnaya biologiya i meditsiny. Kniga 1. Gennye tekhnologii i klonirovanie. Ed. VP Puzyreva, KN Yarygina, VN Yarygina, VV Semchenko. Omsk-Moscow-Tomsk: Omsk regional printing house; 2012. 296] (in Russian).</mixed-citation><mixed-citation xml:lang="en">Семченко В.В., Ерениев С.И., Степанов С.С., Дыгай А.М., Ощепков В.Г., Лебедев И.Н. Регенеративная биология и медицины. Книга 1. Генные технологии и клонирование. Под ред. В.П. Пузырева, К.Н.Ярыгина, В.Н.Ярыгина, В.В.Семченко. Омск-Москва-Томск: Омская областная типография; 2012. 296 [Semchenko VV, Ereniev SI, Stepanov SS, Dygai AM, Oshchepkov VG, Lebedev IN. Regenerativnaya biologiya i meditsiny. Kniga 1. Gennye tekhnologii i klonirovanie. Ed. VP Puzyreva, KN Yarygina, VN Yarygina, VV Semchenko. Omsk-Moscow-Tomsk: Omsk regional printing house; 2012. 296] (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Тер-Асатуров Г.П., Лекишвили М.В., Бигвава А.Т., Аджиев К.С., и др. Сравнительное экспериментально-морфологическое исследование эффективности биологических остеопластических материалов а замещении костных дефектов. Клеточная трансплантология и тканевая инженерия. 2012; 7(1): 81–5 [Ter-Asaturov GP, Lekishvili MV, Bigvava AT, Adzhiev KS, et al. Comparative experimental and morphological study of biological osteoplastic materials in bone defects repair. Cell Transplantology and Tissue Engineering. 2012; 7(1): 81–5] (in Russian).</mixed-citation><mixed-citation xml:lang="en">Тер-Асатуров Г.П., Лекишвили М.В., Бигвава А.Т., Аджиев К.С., и др. Сравнительное экспериментально-морфологическое исследование эффективности биологических остеопластических материалов а замещении костных дефектов. Клеточная трансплантология и тканевая инженерия. 2012; 7(1): 81–5 [Ter-Asaturov GP, Lekishvili MV, Bigvava AT, Adzhiev KS, et al. Comparative experimental and morphological study of biological osteoplastic materials in bone defects repair. Cell Transplantology and Tissue Engineering. 2012; 7(1): 81–5] (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Третьяков А.А., Хижняк И.И., Стадников А.А., Неверов А.Н. Ликвидация остаточных полостей в печени при помощи наноразмерного биокомпозита «ЛитАр». Медицинский вестник Башкортостана. 2015; 10(1):72–6 [Tretiakov AA, Khizhnyak II, Stadnikov AA, Neverov AN. Elimination of residual cavities in the liver using nano biocomposite «Litar». Bashkortostan Medical Journal. 2015; 10(1):72–6] (in Russian).</mixed-citation><mixed-citation xml:lang="en">Третьяков А.А., Хижняк И.И., Стадников А.А., Неверов А.Н. Ликвидация остаточных полостей в печени при помощи наноразмерного биокомпозита «ЛитАр». Медицинский вестник Башкортостана. 2015; 10(1):72–6 [Tretiakov AA, Khizhnyak II, Stadnikov AA, Neverov AN. Elimination of residual cavities in the liver using nano biocomposite «Litar». Bashkortostan Medical Journal. 2015; 10(1):72–6] (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Хабаров В.Н., Бойко П.Я., Селянин М.А. Гиалуроновая кислота: получение, свойства, применение в биологии и медицине. М.: Практическая медицина; 2012. 250 [Khabarov VN, Boiko PYa, Selyanin MA. Gialuronovaya kislota: poluchenie, svoistva, primenenie v biologii i meditsine. Moscow: Prakticheskaya meditsina; 2012. 250] (in Russian).</mixed-citation><mixed-citation xml:lang="en">Хабаров В.Н., Бойко П.Я., Селянин М.А. Гиалуроновая кислота: получение, свойства, применение в биологии и медицине. М.: Практическая медицина; 2012. 250 [Khabarov VN, Boiko PYa, Selyanin MA. Gialuronovaya kislota: poluchenie, svoistva, primenenie v biologii i meditsine. Moscow: Prakticheskaya meditsina; 2012. 250] (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Шумаков В.И., Севастьянов В.И. Биополимерные матриксы для искусственных органов и тканей. Здравоохранение и медицинская техника. 2003; 4: 30–2 [Shumakov VI, Sevast'yanov VI. Biopolimernye matriksy dlya iskusstvennykh organov i tkanei. Zdravookhranenie i meditsinskaya tekhnika. 2003; 4: 30–2] (in Russian).</mixed-citation><mixed-citation xml:lang="en">Шумаков В.И., Севастьянов В.И. Биополимерные матриксы для искусственных органов и тканей. Здравоохранение и медицинская техника. 2003; 4: 30–2 [Shumakov VI, Sevast'yanov VI. Biopolimernye matriksy dlya iskusstvennykh organov i tkanei. Zdravookhranenie i meditsinskaya tekhnika. 2003; 4: 30–2] (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Archana D, Singh BK, Dutta J, Dutta PK. In vivo evaluation of chitosan-PVP-titanium dioxide nanocomposite as wound dressing material. Carbohydrate Polymers. 2013 Jun;95(1):530–9. doi: 10.1016/j.carbpol.2013.03.034</mixed-citation><mixed-citation xml:lang="en">Archana D, Singh BK, Dutta J, Dutta PK. In vivo evaluation of chitosan-PVP-titanium dioxide nanocomposite as wound dressing material. Carbohydrate Polymers. 2013 Jun;95(1):530–9. doi: 10.1016/j.carbpol.2013.03.034</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Baas J, Lamberg A, Jensen TB, Elmengaard B, Soballe K. The bovine bone protein lyophilisate Colloss improves fixation of allografted implantsan experimental study in dogs. Acta Orthopaedica. 2006 Jan;77(5):791–8. doi: 10.1080/17453670610013015</mixed-citation><mixed-citation xml:lang="en">Baas J, Lamberg A, Jensen TB, Elmengaard B, Soballe K. The bovine bone protein lyophilisate Colloss improves fixation of allografted implantsan experimental study in dogs. Acta Orthopaedica. 2006 Jan;77(5):791–8. doi: 10.1080/17453670610013015</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Barradas A, Yuan H, van Blitterswijk C, Habibovic P. Osteoinductive biomaterials: current knowledge of properties, experimental models and biological mechanisms. European Cells and Materials. 2011 May 22;21(1):407–29. doi: 10.22203/ecm.v021a31</mixed-citation><mixed-citation xml:lang="en">Barradas A, Yuan H, van Blitterswijk C, Habibovic P. Osteoinductive biomaterials: current knowledge of properties, experimental models and biological mechanisms. European Cells and Materials. 2011 May 22;21(1):407–29. doi: 10.22203/ecm.v021a31</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Bauer D, Wasmuth S, Hennig M, Baehler H, Steuhl K-P, Heiligenhaus A. Amniotic Membrane Transplantation Induces Apoptosis in T Lymphocytes in Murine Corneas with Experimental Herpetic Stromal Keratitis. Investigative Opthalmology &amp; Visual Science. 2009 Jul 1;50(7):3188–9.</mixed-citation><mixed-citation xml:lang="en">Bauer D, Wasmuth S, Hennig M, Baehler H, Steuhl K-P, Heiligenhaus A. Amniotic Membrane Transplantation Induces Apoptosis in T Lymphocytes in Murine Corneas with Experimental Herpetic Stromal Keratitis. Investigative Opthalmology &amp; Visual Science. 2009 Jul 1;50(7):3188–9.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Bello YM, Falabella AF, Eaglstein WH. Tissue- Engineered Skin. American Journal of Clinical Dermatology. 2001;2(5):305–13. doi: 10.2165/00128071-200102050-00005</mixed-citation><mixed-citation xml:lang="en">Bello YM, Falabella AF, Eaglstein WH. Tissue- Engineered Skin. American Journal of Clinical Dermatology. 2001;2(5):305–13. doi: 10.2165/00128071-200102050-00005</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Bichara DA, O’Sullivan N-A, Pomerantseva I, Zhao X, Sundback CA, Vacanti JP, et al. The Tissue-Engineered Auricle: Past, Present, and Future. Tissue Engineering Part B: Reviews. 2012 Feb;18(1):51–61. doi: 10.1089/ten.teb.2011.0326</mixed-citation><mixed-citation xml:lang="en">Bichara DA, O’Sullivan N-A, Pomerantseva I, Zhao X, Sundback CA, Vacanti JP, et al. The Tissue-Engineered Auricle: Past, Present, and Future. Tissue Engineering Part B: Reviews. 2012 Feb;18(1):51–61. doi: 10.1089/ten.teb.2011.0326</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Bly RA, Bhrany AD, Murakami CS, Sie KCY. Microtia Reconstruction. Facial Plastic Surgery Clinics of North America. 2016 Nov;24(4):577–91. doi: 10.1016/j.fsc.2016.06.011</mixed-citation><mixed-citation xml:lang="en">Bly RA, Bhrany AD, Murakami CS, Sie KCY. Microtia Reconstruction. Facial Plastic Surgery Clinics of North America. 2016 Nov;24(4):577–91. doi: 10.1016/j.fsc.2016.06.011</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Bolchakov IN, Patlataya NN, Levenets AA. «Bolchital » – a new innovative product in maxillofacial surgery. Eur. J. natural History. 2009;2:52–4.</mixed-citation><mixed-citation xml:lang="en">Bolchakov IN, Patlataya NN, Levenets AA. «Bolchital » – a new innovative product in maxillofacial surgery. Eur. J. natural History. 2009;2:52–4.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Catros S, Guillemot F, Nandakumar A, Ziane S, Moroni L, Habibovic P, et al. Layer-by-Layer Tissue Microfabrication Supports Cell Proliferation In Vitro and In Vivo. Tissue Engineering Part C: Methods. 2012 Jan;18(1):62–70. doi: 10.1089/ten.tec.2011.0382</mixed-citation><mixed-citation xml:lang="en">Catros S, Guillemot F, Nandakumar A, Ziane S, Moroni L, Habibovic P, et al. Layer-by-Layer Tissue Microfabrication Supports Cell Proliferation In Vitro and In Vivo. Tissue Engineering Part C: Methods. 2012 Jan;18(1):62–70. doi: 10.1089/ten.tec.2011.0382</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Cirman T, Beltram M, Schollmayer P, Rožman P, Kreft ME. Amniotic membrane properties and current practice of amniotic membrane use in ophthalmology in Slovenia. Cell and Tissue Banking. 2013 Dec 19;15(2):177–92. doi: 10.1007/s10561-013-9417-6</mixed-citation><mixed-citation xml:lang="en">Cirman T, Beltram M, Schollmayer P, Rožman P, Kreft ME. Amniotic membrane properties and current practice of amniotic membrane use in ophthalmology in Slovenia. Cell and Tissue Banking. 2013 Dec 19;15(2):177–92. doi: 10.1007/s10561-013-9417-6</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Cooper LJ, Kinoshita S, German M, Koizumi N, Nakamura T, Fullwood NJ. An Investigation into the Composition of Amniotic Membrane Used for Ocular Surface Reconstruction. Cornea. 2005 Aug;24(6):722–9. doi: 10.1097/01.ico.0000154237.49112.29</mixed-citation><mixed-citation xml:lang="en">Cooper LJ, Kinoshita S, German M, Koizumi N, Nakamura T, Fullwood NJ. An Investigation into the Composition of Amniotic Membrane Used for Ocular Surface Reconstruction. Cornea. 2005 Aug;24(6):722–9. doi: 10.1097/01.ico.0000154237.49112.29</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Dosadina EE, Savelyeva EE, Belov AA. The effect of immobilization, drying and storage on the activity of proteinases immobilized on modified cellulose and chitosan. Process Biochemistry. 2018 Jan;64(1):213–20. doi: 10.1016/j.procbio.2017.10.002</mixed-citation><mixed-citation xml:lang="en">Dosadina EE, Savelyeva EE, Belov AA. The effect of immobilization, drying and storage on the activity of proteinases immobilized on modified cellulose and chitosan. Process Biochemistry. 2018 Jan;64(1):213–20. doi: 10.1016/j.procbio.2017.10.002</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Dua HS, Azuara-Blanco A. Amniotic membrane transplantation. Br J Ophthalmol. 1999 1999 Jun;83(6):748–52.</mixed-citation><mixed-citation xml:lang="en">Dua HS, Azuara-Blanco A. Amniotic membrane transplantation. Br J Ophthalmol. 1999 1999 Jun;83(6):748–52.</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Einhorn TA. Clinical applications of recombinant human BMPs: early experience and future development. J Bone Joint Surg Am. 2003;85-A(3):82–8.</mixed-citation><mixed-citation xml:lang="en">Einhorn TA. Clinical applications of recombinant human BMPs: early experience and future development. J Bone Joint Surg Am. 2003;85-A(3):82–8.</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Finkemeier CG. Current concepts review: Bonegrafting and bone-graft substitutes. The Journal of Bone and Joint Surgery-American Volume. 2002 Mar;84(3):454–64.</mixed-citation><mixed-citation xml:lang="en">Finkemeier CG. Current concepts review: Bonegrafting and bone-graft substitutes. The Journal of Bone and Joint Surgery-American Volume. 2002 Mar;84(3):454–64.</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Garfias Y, Zaga-Clavellina V, Vadillo-Ortega F, Osorio M, Jimenez-Martinez MC. Amniotic Membrane is an Immunosuppressor of Peripheral Blood Mononuclear Cells. Immunological Investigations. 2010 Nov 16;40(2):183–96. doi: 10.3109/08820139.2010.532266</mixed-citation><mixed-citation xml:lang="en">Garfias Y, Zaga-Clavellina V, Vadillo-Ortega F, Osorio M, Jimenez-Martinez MC. Amniotic Membrane is an Immunosuppressor of Peripheral Blood Mononuclear Cells. Immunological Investigations. 2010 Nov 16;40(2):183–96. doi: 10.3109/08820139.2010.532266</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Habibovic P, Yuan H, van den Doel M, Sees TM, van Blitterswijk CA, de Groot K. Relevance of Osteoinductive Biomaterials in Critical-Sized Orthotopic Defect. Journal of Orthopaedic Research. 2006 Apr 4;24(5):867–76. doi: 10.1002/jor.20115</mixed-citation><mixed-citation xml:lang="en">Habibovic P, Yuan H, van den Doel M, Sees TM, van Blitterswijk CA, de Groot K. Relevance of Osteoinductive Biomaterials in Critical-Sized Orthotopic Defect. Journal of Orthopaedic Research. 2006 Apr 4;24(5):867–76. doi: 10.1002/jor.20115</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Habraken W, Habibovic P, Epple M, Bohner M. Calcium phosphates in biomedical applications: materials for the future? Materials Today. 2016 Mar;19(2):69–87. doi: 10.1016/j.mattod.2015.10.008</mixed-citation><mixed-citation xml:lang="en">Habraken W, Habibovic P, Epple M, Bohner M. Calcium phosphates in biomedical applications: materials for the future? Materials Today. 2016 Mar;19(2):69–87. doi: 10.1016/j.mattod.2015.10.008</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Hench L. Bioceramics. J. Amer. Ceram. Soc. 1998;81(7):1705–28.</mixed-citation><mixed-citation xml:lang="en">Hench L. Bioceramics. J. Amer. Ceram. Soc. 1998;81(7):1705–28.</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">Higa K, Shimmura S, Shimazaki J, Tsubota K. Hyaluronic Acid-CD44 Interaction Mediates the Adhesion of Lymphocytes by Amniotic Membrane Stroma. Cornea. 2005 Mar;24(2):206–12. doi: 10.1097/01.ico.0000133999.45262.83</mixed-citation><mixed-citation xml:lang="en">Higa K, Shimmura S, Shimazaki J, Tsubota K. Hyaluronic Acid-CD44 Interaction Mediates the Adhesion of Lymphocytes by Amniotic Membrane Stroma. Cornea. 2005 Mar;24(2):206–12. doi: 10.1097/01.ico.0000133999.45262.83</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">Iwata H, Sakano S, Itoh T, Bauer TW. Demineralized Bone Matrix and Native Bone Morphogenetic Protein in Orthopaedic Surgery. Clinical Orthopaedics and Related Research. 2002 Feb;395:99–109. doi: 10.1097/00003086-200202000-00010</mixed-citation><mixed-citation xml:lang="en">Iwata H, Sakano S, Itoh T, Bauer TW. Demineralized Bone Matrix and Native Bone Morphogenetic Protein in Orthopaedic Surgery. Clinical Orthopaedics and Related Research. 2002 Feb;395:99–109. doi: 10.1097/00003086-200202000-00010</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">Jansen LA, De Caigny P, Guay NA, Lineaweaver WC, Shokrollahi K. The Evidence Base for the Acellular Dermal Matrix AlloDerm. Annals of Plastic Surgery. 2013 May;70(5):587–94. doi: 10.1097/sap.0b013e31827a2d23</mixed-citation><mixed-citation xml:lang="en">Jansen LA, De Caigny P, Guay NA, Lineaweaver WC, Shokrollahi K. The Evidence Base for the Acellular Dermal Matrix AlloDerm. Annals of Plastic Surgery. 2013 May;70(5):587–94. doi: 10.1097/sap.0b013e31827a2d23</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">Jayakumar R, Prabaharan M, Sudheesh Kumar PT, Nair SV, Tamura H. Biomaterials based on chitin and chitosan in wound dressing applications. Biotechnology Advances [Internet]. 2011 May [cited 2019 Dec 1];29(3):322–37. doi: 10.1016/j.biotechadv.2011.01.005</mixed-citation><mixed-citation xml:lang="en">Jayakumar R, Prabaharan M, Sudheesh Kumar PT, Nair SV, Tamura H. Biomaterials based on chitin and chitosan in wound dressing applications. Biotechnology Advances [Internet]. 2011 May [cited 2019 Dec 1];29(3):322–37. doi: 10.1016/j.biotechadv.2011.01.005</mixed-citation></citation-alternatives></ref><ref id="cit50"><label>50</label><citation-alternatives><mixed-citation xml:lang="ru">Jin CZ, Park SR, Choi BH, Lee K-Y, Kang CK, Min B-H. Human Amniotic Membrane as a Delivery Matrix for Articular Cartilage Repair. Tissue Engineering. 2007 Apr;13(4):693–702. 49. Johnson EE, Urist MR. Human Bone Morphogenetic Protein Allografting for Reconstruction of Femoral Nonunion. Clinical Orthopaedics and Related Research. 2000 Feb;371:61–74</mixed-citation><mixed-citation xml:lang="en">Jin CZ, Park SR, Choi BH, Lee K-Y, Kang CK, Min B-H. Human Amniotic Membrane as a Delivery Matrix for Articular Cartilage Repair. Tissue Engineering. 2007 Apr;13(4):693–702. 49. Johnson EE, Urist MR. Human Bone Morphogenetic Protein Allografting for Reconstruction of Femoral Nonunion. Clinical Orthopaedics and Related Research. 2000 Feb;371:61–74</mixed-citation></citation-alternatives></ref><ref id="cit51"><label>51</label><citation-alternatives><mixed-citation xml:lang="ru">Kasyanov VA, Pereira FDAS, Parfenov VA, Kudan EV, Bulanova EA, Khesuani YD, et al. Development and Implantation of a Biocompatible Auricular Prosthesis. Biomedical Engineering. 2016 Mar;49(6):327–30.</mixed-citation><mixed-citation xml:lang="en">Kasyanov VA, Pereira FDAS, Parfenov VA, Kudan EV, Bulanova EA, Khesuani YD, et al. Development and Implantation of a Biocompatible Auricular Prosthesis. Biomedical Engineering. 2016 Mar;49(6):327–30.</mixed-citation></citation-alternatives></ref><ref id="cit52"><label>52</label><citation-alternatives><mixed-citation xml:lang="ru">Kim JC, Tseng SCG. The effects on inhibition of corneal neovascularization after human amniotic membrane transplantation in severely damaged rabbit corneas. Korean Journal of Ophthalmology. 1995;9(1):32–46. doi: 10.3341/kjo.1995.9.1.32</mixed-citation><mixed-citation xml:lang="en">Kim JC, Tseng SCG. The effects on inhibition of corneal neovascularization after human amniotic membrane transplantation in severely damaged rabbit corneas. Korean Journal of Ophthalmology. 1995;9(1):32–46. doi: 10.3341/kjo.1995.9.1.32</mixed-citation></citation-alternatives></ref><ref id="cit53"><label>53</label><citation-alternatives><mixed-citation xml:lang="ru">Meller D, Pires RT, Mack RJ, Figueiredo F, Heiligenhaus A, Park WC, et al. Amniotic membrane transplantation for acute chemical or thermal burns. Ophthalmology. 2000 May;107(5):980–9. doi: 10.1016/s0161-6420(00)00024-5</mixed-citation><mixed-citation xml:lang="en">Meller D, Pires RT, Mack RJ, Figueiredo F, Heiligenhaus A, Park WC, et al. Amniotic membrane transplantation for acute chemical or thermal burns. Ophthalmology. 2000 May;107(5):980–9. doi: 10.1016/s0161-6420(00)00024-5</mixed-citation></citation-alternatives></ref><ref id="cit54"><label>54</label><citation-alternatives><mixed-citation xml:lang="ru">Meller D, Tseng SC. Conjunctival epithelial cell differentiation on amniotic membrane. Invest Ophthalmol Vis Sci. 1999 Apr;40(5):878–86.</mixed-citation><mixed-citation xml:lang="en">Meller D, Tseng SC. Conjunctival epithelial cell differentiation on amniotic membrane. Invest Ophthalmol Vis Sci. 1999 Apr;40(5):878–86.</mixed-citation></citation-alternatives></ref><ref id="cit55"><label>55</label><citation-alternatives><mixed-citation xml:lang="ru">Naumann A. Porous polyethylene implants for ear recomstruction of middle high-grade defects. HNO. 2011 Feb;59(2):197–212.</mixed-citation><mixed-citation xml:lang="en">Naumann A. Porous polyethylene implants for ear recomstruction of middle high-grade defects. HNO. 2011 Feb;59(2):197–212.</mixed-citation></citation-alternatives></ref><ref id="cit56"><label>56</label><citation-alternatives><mixed-citation xml:lang="ru">Rosenthal RK, Folkman J, Glowacki J. Demineralized Bone Implants for Nonunion Fractures, Bone Cysts, and Fibrous Lesions. Clinical Orthopaedics and Related Research. 1999 Jul;364:61–9. doi: 10.1097/00003086-199907000-00009</mixed-citation><mixed-citation xml:lang="en">Rosenthal RK, Folkman J, Glowacki J. Demineralized Bone Implants for Nonunion Fractures, Bone Cysts, and Fibrous Lesions. Clinical Orthopaedics and Related Research. 1999 Jul;364:61–9. doi: 10.1097/00003086-199907000-00009</mixed-citation></citation-alternatives></ref><ref id="cit57"><label>57</label><citation-alternatives><mixed-citation xml:lang="ru">Sachlos E, Czernuszka J. Making Tissue Engineering Scaffolds Work. Review: The application of solid freeform fabrication technology to the production of tissue engineering scaffolds. European Cells and Materials. 2003 Jun 30;5:29–40. doi: 10.22203/ecm.v005a03</mixed-citation><mixed-citation xml:lang="en">Sachlos E, Czernuszka J. Making Tissue Engineering Scaffolds Work. Review: The application of solid freeform fabrication technology to the production of tissue engineering scaffolds. European Cells and Materials. 2003 Jun 30;5:29–40. doi: 10.22203/ecm.v005a03</mixed-citation></citation-alternatives></ref><ref id="cit58"><label>58</label><citation-alternatives><mixed-citation xml:lang="ru">Shameli K, Ahmad MV,Yunis WZ, Rustaiyan A, Ibrahim NA, Mohsen Z, Abdollahi J. Green synthesis of silver/montmorillonite/chitosan bionanocomposites using the UV irradiation method and evaluation of antibacterial activity. International Journal of Nanomedicine. 2010 Oct;5(1):875–87.</mixed-citation><mixed-citation xml:lang="en">Shameli K, Ahmad MV,Yunis WZ, Rustaiyan A, Ibrahim NA, Mohsen Z, Abdollahi J. Green synthesis of silver/montmorillonite/chitosan bionanocomposites using the UV irradiation method and evaluation of antibacterial activity. International Journal of Nanomedicine. 2010 Oct;5(1):875–87.</mixed-citation></citation-alternatives></ref><ref id="cit59"><label>59</label><citation-alternatives><mixed-citation xml:lang="ru">Soto K, Urist MR. Induced regeneration of calvaria by bone morphogenetic protein(BMP) in dog. Clinical Orthopaedics and Related Research. 1985;197:301–11. doi: 10.1097/00003086-198507000-00037</mixed-citation><mixed-citation xml:lang="en">Soto K, Urist MR. Induced regeneration of calvaria by bone morphogenetic protein(BMP) in dog. Clinical Orthopaedics and Related Research. 1985;197:301–11. doi: 10.1097/00003086-198507000-00037</mixed-citation></citation-alternatives></ref><ref id="cit60"><label>60</label><citation-alternatives><mixed-citation xml:lang="ru">Takikawa S, Bauer TW, Konbic H. A comparative evalution of the osteoinductivity of two formulations of human demineralized bone matrix. Trans. Soc. Biomat. 2001; 24:302.</mixed-citation><mixed-citation xml:lang="en">Takikawa S, Bauer TW, Konbic H. A comparative evalution of the osteoinductivity of two formulations of human demineralized bone matrix. Trans. Soc. Biomat. 2001; 24:302.</mixed-citation></citation-alternatives></ref><ref id="cit61"><label>61</label><citation-alternatives><mixed-citation xml:lang="ru">Tsai CC, Lin SD, Lai SC, Lin TM. The use of composite acellular allodermis-ultrathin autograft on joint area in major burn patients--one year follow-up. Kaohsiung J Med Sci. 1999 Nov;15(11):651-8.</mixed-citation><mixed-citation xml:lang="en">Tsai CC, Lin SD, Lai SC, Lin TM. The use of composite acellular allodermis-ultrathin autograft on joint area in major burn patients--one year follow-up. Kaohsiung J Med Sci. 1999 Nov;15(11):651-8.</mixed-citation></citation-alternatives></ref><ref id="cit62"><label>62</label><citation-alternatives><mixed-citation xml:lang="ru">Walter CJ, Dumville JC, Sharp CA, Page T. Systematic review and meta-analysis of wound dressings in the prevention of surgical-site infections in surgical wounds healing by primary intention. British Journal of Surgery. 2012 Jul 6;99(9):1185–94. doi: 10.1002/bjs.8812</mixed-citation><mixed-citation xml:lang="en">Walter CJ, Dumville JC, Sharp CA, Page T. Systematic review and meta-analysis of wound dressings in the prevention of surgical-site infections in surgical wounds healing by primary intention. British Journal of Surgery. 2012 Jul 6;99(9):1185–94. doi: 10.1002/bjs.8812</mixed-citation></citation-alternatives></ref><ref id="cit63"><label>63</label><citation-alternatives><mixed-citation xml:lang="ru">Wang K, Hou W-D, Wang X, Han C, Vuletic I, Su N, et al. Overcoming foreign-body reaction through nanotopography: Biocompatibility and immunoisolation properties of a nanofibrous membrane. Biomaterials. 2016 Sep;102:249–58. doi: 10.1016/j.biomaterials.2016.06.028</mixed-citation><mixed-citation xml:lang="en">Wang K, Hou W-D, Wang X, Han C, Vuletic I, Su N, et al. Overcoming foreign-body reaction through nanotopography: Biocompatibility and immunoisolation properties of a nanofibrous membrane. Biomaterials. 2016 Sep;102:249–58. doi: 10.1016/j.biomaterials.2016.06.028</mixed-citation></citation-alternatives></ref><ref id="cit64"><label>64</label><citation-alternatives><mixed-citation xml:lang="ru">Wozney JM. Overview of Bone Morphogenetic Proteins. Spine. 2002 Aug;27(Supplement):S2–8.</mixed-citation><mixed-citation xml:lang="en">Wozney JM. Overview of Bone Morphogenetic Proteins. Spine. 2002 Aug;27(Supplement):S2–8.</mixed-citation></citation-alternatives></ref><ref id="cit65"><label>65</label><citation-alternatives><mixed-citation xml:lang="ru">Yuan H, Fernandes H, Habibovic P, de Boer J, Barradas AMC, de Ruiter A, et al. Osteoinductive ceramics as a synthetic alternative to autologous bone grafting. Proceedings of the National Academy of Sciences. 2010 Jul 19;107(31):13614–9. doi: 10.1073/pnas.1003600107</mixed-citation><mixed-citation xml:lang="en">Yuan H, Fernandes H, Habibovic P, de Boer J, Barradas AMC, de Ruiter A, et al. Osteoinductive ceramics as a synthetic alternative to autologous bone grafting. Proceedings of the National Academy of Sciences. 2010 Jul 19;107(31):13614–9. doi: 10.1073/pnas.1003600107</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
